diff --git a/src/video_core/renderer_vulkan/vk_pipeline_cache.cpp b/src/video_core/renderer_vulkan/vk_pipeline_cache.cpp
index 6ed0068c7b..2af6f29a9b 100644
--- a/src/video_core/renderer_vulkan/vk_pipeline_cache.cpp
+++ b/src/video_core/renderer_vulkan/vk_pipeline_cache.cpp
@@ -63,6 +63,8 @@ using VideoCommon::GenericEnvironment;
 using VideoCommon::GraphicsEnvironment;
 
 constexpr u32 CACHE_VERSION = 18;
+constexpr size_t VULKAN_CACHE_FLUSH_PIPELINES = 128;
+constexpr size_t VULKAN_CACHE_FLUSH_MIN_SECONDS = 30;
 constexpr std::array<char, 8> VULKAN_CACHE_MAGIC_NUMBER{'y', 'u', 'z', 'u', 'v', 'k', 'c', 'h'};
 
 template <typename Container>
@@ -705,6 +707,10 @@ void PipelineCache::LoadDiskResources(u64 title_id, std::stop_token stop_loading
     if (use_vulkan_pipeline_cache) {
         SerializeVulkanPipelineCache(vulkan_pipeline_cache_filename, vulkan_pipeline_cache,
                                      CACHE_VERSION);
+        size_t size = 0;
+        vulkan_pipeline_cache.Read(&size, nullptr);
+        last_cache_size.store(size, std::memory_order_relaxed);
+        last_flush = std::chrono::steady_clock::now();
     }
 
     if (state.statistics) {
@@ -712,6 +718,35 @@ void PipelineCache::LoadDiskResources(u64 title_id, std::stop_token stop_loading
     }
 }
 
+void PipelineCache::QueueVulkanPipelineCacheFlush() {
+    if (!use_vulkan_pipeline_cache || vulkan_pipeline_cache_filename.empty()) {
+        return;
+    }
+    if (++pipelines_since_flush < VULKAN_CACHE_FLUSH_PIPELINES) {
+        return;
+    }
+    const auto now = std::chrono::steady_clock::now();
+    const auto megabytes = last_cache_size.load(std::memory_order_relaxed) / (1024 * 1024);
+    const std::chrono::seconds interval{
+        std::max<size_t>(VULKAN_CACHE_FLUSH_MIN_SECONDS, megabytes)};
+    if (last_flush.time_since_epoch().count() != 0 && now - last_flush < interval) {
+        return;
+    }
+    if (flush_in_flight.exchange(true, std::memory_order_acq_rel)) {
+        return;
+    }
+    pipelines_since_flush = 0;
+    last_flush = now;
+    serialization_thread.QueueWork([this] {
+        SerializeVulkanPipelineCache(vulkan_pipeline_cache_filename, vulkan_pipeline_cache,
+                                     CACHE_VERSION);
+        size_t size = 0;
+        vulkan_pipeline_cache.Read(&size, nullptr);
+        last_cache_size.store(size, std::memory_order_relaxed);
+        flush_in_flight.store(false, std::memory_order_release);
+    });
+}
+
 GraphicsPipeline* PipelineCache::CurrentGraphicsPipelineSlowPath() {
     const auto [pair, is_new]{graphics_cache.try_emplace(graphics_key)};
     auto& pipeline{pair->second};
@@ -750,7 +785,7 @@ std::unique_ptr<GraphicsPipeline> PipelineCache::CreateGraphicsPipeline(
     std::span<Shader::Environment* const> envs, PipelineStatistics* statistics,
     bool build_in_parallel) try {
     auto hash = key.Hash();
-    LOG_INFO(Render_Vulkan, "{:#016x}", hash);
+    LOG_DEBUG(Render_Vulkan, "{:#016x}", hash);
     size_t env_index{0};
     std::array<Shader::IR::Program, Maxwell::MaxShaderProgram> programs;
     const bool uses_vertex_a{key.unique_hashes[0] != 0};
@@ -886,6 +921,7 @@ std::unique_ptr<GraphicsPipeline> PipelineCache::CreateGraphicsPipeline() {
         }
         SerializePipeline(key, env_ptrs, pipeline_cache_filename, CACHE_VERSION);
     });
+    QueueVulkanPipelineCacheFlush();
     return pipeline;
 }
 
@@ -905,6 +941,7 @@ std::unique_ptr<ComputePipeline> PipelineCache::CreateComputePipeline(
         SerializePipeline(key, std::array<const GenericEnvironment*, 1>{&env_},
                           pipeline_cache_filename, CACHE_VERSION);
     });
+    QueueVulkanPipelineCacheFlush();
     return pipeline;
 }
 
@@ -917,7 +954,7 @@ std::unique_ptr<ComputePipeline> PipelineCache::CreateComputePipeline(
         return nullptr;
     }
 
-    LOG_INFO(Render_Vulkan, "{:#016x}", hash);
+    LOG_DEBUG(Render_Vulkan, "{:#016x}", hash);
 
     Shader::Maxwell::Flow::CFG cfg{env, pools.flow_block, env.StartAddress()};
 
diff --git a/src/video_core/renderer_vulkan/vk_pipeline_cache.h b/src/video_core/renderer_vulkan/vk_pipeline_cache.h
index ce89e981d2..9d66b663f5 100644
--- a/src/video_core/renderer_vulkan/vk_pipeline_cache.h
+++ b/src/video_core/renderer_vulkan/vk_pipeline_cache.h
@@ -7,6 +7,8 @@
 #pragma once
 
 #include <array>
+#include <atomic>
+#include <chrono>
 #include <cstddef>
 #include <filesystem>
 #include <memory>
@@ -144,6 +146,8 @@ private:
     vk::PipelineCache LoadVulkanPipelineCache(const std::filesystem::path& filename,
                                               u32 expected_cache_version);
 
+    void QueueVulkanPipelineCacheFlush();
+
     const Device& device;
     Scheduler& scheduler;
     DescriptorPool& descriptor_pool;
@@ -171,6 +175,10 @@ private:
 
     std::filesystem::path vulkan_pipeline_cache_filename;
     vk::PipelineCache vulkan_pipeline_cache;
+    size_t pipelines_since_flush{};
+    std::chrono::steady_clock::time_point last_flush{};
+    std::atomic<size_t> last_cache_size{};
+    std::atomic_bool flush_in_flight{};
 
     Common::ThreadWorker workers;
     Common::ThreadWorker serialization_thread;