diff --git a/CMakeLists.txt b/CMakeLists.txt
index 86c0dacddd..4ab08739f7 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -199,9 +199,6 @@ cmake_dependent_option(ENABLE_LIBUSB "Enable the use of LibUSB" ON "WIN32 OR PLA
 cmake_dependent_option(ENABLE_OPENGL "Enable OpenGL" ON "NOT (WIN32 AND ARCHITECTURE_arm64) AND NOT APPLE" OFF)
 mark_as_advanced(FORCE ENABLE_OPENGL)
 
-option(ENABLE_VULKAN "Enable Vulkan" ON)
-mark_as_advanced(FORCE ENABLE_VULKAN)
-
 option(ENABLE_WEB_SERVICE "Enable web services (telemetry, etc.)" ON)
 option(ENABLE_WIFI_SCAN "Enable WiFi scanning" OFF)
 
diff --git a/docs/Options.md b/docs/Options.md
index b26606ee76..3eb6effe92 100644
--- a/docs/Options.md
+++ b/docs/Options.md
@@ -74,8 +74,6 @@ The following options are desktop only.
 - `ENABLE_OPENGL` (ON) Enable the OpenGL graphics backend
   - Unavailable on Windows/ARM64
   - You probably shouldn't turn this off.
-- `ENABLE_VULKAN` (ON) Enable the Vulkan graphics backend
-  - Only turn this off for builds that depend entirely on OpenGL.
 
 ### Qt
 
diff --git a/src/qt_common/CMakeLists.txt b/src/qt_common/CMakeLists.txt
index ec8afcd690..176e38e09f 100644
--- a/src/qt_common/CMakeLists.txt
+++ b/src/qt_common/CMakeLists.txt
@@ -85,9 +85,6 @@ target_link_libraries(qt_common PRIVATE gamemode::headers frontend_common)
 if (ENABLE_OPENGL)
     target_compile_definitions(qt_common PUBLIC HAS_OPENGL)
 endif()
-if (ENABLE_VULKAN)
-    target_compile_definitions(qt_common PUBLIC HAS_VULKAN)
-endif()
 
 if (UNIX AND NOT APPLE)
     if (DEFINED Qt6Gui_PRIVATE_INCLUDE_DIRS)
diff --git a/src/qt_common/config/shared_translation.cpp b/src/qt_common/config/shared_translation.cpp
index e53d9624d2..d1ed32134c 100644
--- a/src/qt_common/config/shared_translation.cpp
+++ b/src/qt_common/config/shared_translation.cpp
@@ -538,9 +538,7 @@ std::unique_ptr<ComboboxTranslationMap> ComboboxEnumeration(QObject* parent)
                               PAIR(VramUsageMode, Aggressive, tr("Aggressive")),
                           }});
     translations->insert({Settings::EnumMetadata<Settings::RendererBackend>::Index(), {
-#ifdef HAS_VULKAN
         PAIR(RendererBackend, Vulkan, tr("Vulkan")),
-#endif
 #ifdef HAS_OPENGL
         PAIR(RendererBackend, OpenGL_GLSL, tr("OpenGL GLSL")),
         PAIR(RendererBackend, OpenGL_GLASM, tr("OpenGL GLASM (Assembly Shaders, NVIDIA Only)")),
diff --git a/src/video_core/CMakeLists.txt b/src/video_core/CMakeLists.txt
index 7005c98986..3324682639 100644
--- a/src/video_core/CMakeLists.txt
+++ b/src/video_core/CMakeLists.txt
@@ -111,10 +111,108 @@ add_library(video_core STATIC
     rasterizer_interface.h
     renderer_base.cpp
     renderer_base.h
+
+    # Null
     renderer_null/null_rasterizer.cpp
     renderer_null/null_rasterizer.h
     renderer_null/renderer_null.cpp
     renderer_null/renderer_null.h
+
+    # Vulkan
+    renderer_vulkan/present/anti_alias_pass.h
+    renderer_vulkan/present/filters.cpp
+    renderer_vulkan/present/filters.h
+    renderer_vulkan/present/fsr.cpp
+    renderer_vulkan/present/fsr.h
+    renderer_vulkan/present/fxaa.cpp
+    renderer_vulkan/present/fxaa.h
+    renderer_vulkan/present/layer.cpp
+    renderer_vulkan/present/layer.h
+    renderer_vulkan/present/present_push_constants.h
+    renderer_vulkan/present/smaa.cpp
+    renderer_vulkan/present/smaa.h
+    renderer_vulkan/present/util.cpp
+    renderer_vulkan/present/util.h
+    renderer_vulkan/present/window_adapt_pass.cpp
+    renderer_vulkan/present/window_adapt_pass.h
+    renderer_vulkan/blit_image.cpp
+    renderer_vulkan/blit_image.h
+    renderer_vulkan/fixed_pipeline_state.cpp
+    renderer_vulkan/fixed_pipeline_state.h
+    renderer_vulkan/maxwell_to_vk.cpp
+    renderer_vulkan/maxwell_to_vk.h
+    renderer_vulkan/pipeline_helper.h
+    renderer_vulkan/pipeline_statistics.cpp
+    renderer_vulkan/pipeline_statistics.h
+    renderer_vulkan/renderer_vulkan.h
+    renderer_vulkan/renderer_vulkan.cpp
+    renderer_vulkan/vk_blit_screen.cpp
+    renderer_vulkan/vk_blit_screen.h
+    renderer_vulkan/vk_buffer_cache_base.cpp
+    renderer_vulkan/vk_buffer_cache.cpp
+    renderer_vulkan/vk_buffer_cache.h
+    renderer_vulkan/vk_command_pool.cpp
+    renderer_vulkan/vk_command_pool.h
+    renderer_vulkan/vk_compute_pass.cpp
+    renderer_vulkan/vk_compute_pass.h
+    renderer_vulkan/vk_compute_pipeline.cpp
+    renderer_vulkan/vk_compute_pipeline.h
+    renderer_vulkan/vk_descriptor_pool.cpp
+    renderer_vulkan/vk_descriptor_pool.h
+    renderer_vulkan/vk_fence_manager.cpp
+    renderer_vulkan/vk_fence_manager.h
+    renderer_vulkan/vk_graphics_pipeline.cpp
+    renderer_vulkan/vk_graphics_pipeline.h
+    renderer_vulkan/vk_master_semaphore.cpp
+    renderer_vulkan/vk_master_semaphore.h
+    renderer_vulkan/vk_pipeline_cache.cpp
+    renderer_vulkan/vk_pipeline_cache.h
+    renderer_vulkan/vk_present_manager.cpp
+    renderer_vulkan/vk_present_manager.h
+    renderer_vulkan/vk_query_cache.cpp
+    renderer_vulkan/vk_query_cache.h
+    renderer_vulkan/vk_rasterizer.cpp
+    renderer_vulkan/vk_rasterizer.h
+    renderer_vulkan/vk_render_pass_cache.cpp
+    renderer_vulkan/vk_render_pass_cache.h
+    renderer_vulkan/vk_resource_pool.cpp
+    renderer_vulkan/vk_resource_pool.h
+    renderer_vulkan/vk_scheduler.cpp
+    renderer_vulkan/vk_scheduler.h
+    renderer_vulkan/vk_shader_util.cpp
+    renderer_vulkan/vk_shader_util.h
+    renderer_vulkan/vk_staging_buffer_pool.cpp
+    renderer_vulkan/vk_staging_buffer_pool.h
+    renderer_vulkan/vk_state_tracker.cpp
+    renderer_vulkan/vk_state_tracker.h
+    renderer_vulkan/vk_swapchain.cpp
+    renderer_vulkan/vk_swapchain.h
+    renderer_vulkan/vk_texture_cache.cpp
+    renderer_vulkan/vk_texture_cache.h
+    renderer_vulkan/vk_texture_cache_base.cpp
+    renderer_vulkan/vk_turbo_mode.cpp
+    renderer_vulkan/vk_turbo_mode.h
+    renderer_vulkan/vk_update_descriptor.cpp
+    renderer_vulkan/vk_update_descriptor.h
+    vulkan_common/vulkan_debug_callback.cpp
+    vulkan_common/vulkan_debug_callback.h
+    vulkan_common/vulkan_device.cpp
+    vulkan_common/vulkan_device.h
+    vulkan_common/vulkan_instance.cpp
+    vulkan_common/vulkan_instance.h
+    vulkan_common/vulkan_library.cpp
+    vulkan_common/vulkan_library.h
+    vulkan_common/vulkan_memory_allocator.cpp
+    vulkan_common/vulkan_memory_allocator.h
+    vulkan_common/vulkan_surface.cpp
+    vulkan_common/vulkan_surface.h
+    vulkan_common/vulkan_wrapper.cpp
+    vulkan_common/vulkan_wrapper.h
+    vulkan_common/nsight_aftermath_tracker.cpp
+    vulkan_common/nsight_aftermath_tracker.h
+    vulkan_common/vma.h
+    vulkan_common/vulkan.h
+
     shader_cache.cpp
     shader_cache.h
     shader_environment.cpp
@@ -224,103 +322,6 @@ if (ENABLE_OPENGL)
         renderer_opengl/util_shaders.h
     )
 endif()
-if (ENABLE_VULKAN)
-    target_sources(video_core PRIVATE
-        renderer_vulkan/present/anti_alias_pass.h
-        renderer_vulkan/present/filters.cpp
-        renderer_vulkan/present/filters.h
-        renderer_vulkan/present/fsr.cpp
-        renderer_vulkan/present/fsr.h
-        renderer_vulkan/present/fxaa.cpp
-        renderer_vulkan/present/fxaa.h
-        renderer_vulkan/present/layer.cpp
-        renderer_vulkan/present/layer.h
-        renderer_vulkan/present/present_push_constants.h
-        renderer_vulkan/present/smaa.cpp
-        renderer_vulkan/present/smaa.h
-        renderer_vulkan/present/util.cpp
-        renderer_vulkan/present/util.h
-        renderer_vulkan/present/window_adapt_pass.cpp
-        renderer_vulkan/present/window_adapt_pass.h
-        renderer_vulkan/blit_image.cpp
-        renderer_vulkan/blit_image.h
-        renderer_vulkan/fixed_pipeline_state.cpp
-        renderer_vulkan/fixed_pipeline_state.h
-        renderer_vulkan/maxwell_to_vk.cpp
-        renderer_vulkan/maxwell_to_vk.h
-        renderer_vulkan/pipeline_helper.h
-        renderer_vulkan/pipeline_statistics.cpp
-        renderer_vulkan/pipeline_statistics.h
-        renderer_vulkan/renderer_vulkan.h
-        renderer_vulkan/renderer_vulkan.cpp
-        renderer_vulkan/vk_blit_screen.cpp
-        renderer_vulkan/vk_blit_screen.h
-        renderer_vulkan/vk_buffer_cache_base.cpp
-        renderer_vulkan/vk_buffer_cache.cpp
-        renderer_vulkan/vk_buffer_cache.h
-        renderer_vulkan/vk_command_pool.cpp
-        renderer_vulkan/vk_command_pool.h
-        renderer_vulkan/vk_compute_pass.cpp
-        renderer_vulkan/vk_compute_pass.h
-        renderer_vulkan/vk_compute_pipeline.cpp
-        renderer_vulkan/vk_compute_pipeline.h
-        renderer_vulkan/vk_descriptor_pool.cpp
-        renderer_vulkan/vk_descriptor_pool.h
-        renderer_vulkan/vk_fence_manager.cpp
-        renderer_vulkan/vk_fence_manager.h
-        renderer_vulkan/vk_graphics_pipeline.cpp
-        renderer_vulkan/vk_graphics_pipeline.h
-        renderer_vulkan/vk_master_semaphore.cpp
-        renderer_vulkan/vk_master_semaphore.h
-        renderer_vulkan/vk_pipeline_cache.cpp
-        renderer_vulkan/vk_pipeline_cache.h
-        renderer_vulkan/vk_present_manager.cpp
-        renderer_vulkan/vk_present_manager.h
-        renderer_vulkan/vk_query_cache.cpp
-        renderer_vulkan/vk_query_cache.h
-        renderer_vulkan/vk_rasterizer.cpp
-        renderer_vulkan/vk_rasterizer.h
-        renderer_vulkan/vk_render_pass_cache.cpp
-        renderer_vulkan/vk_render_pass_cache.h
-        renderer_vulkan/vk_resource_pool.cpp
-        renderer_vulkan/vk_resource_pool.h
-        renderer_vulkan/vk_scheduler.cpp
-        renderer_vulkan/vk_scheduler.h
-        renderer_vulkan/vk_shader_util.cpp
-        renderer_vulkan/vk_shader_util.h
-        renderer_vulkan/vk_staging_buffer_pool.cpp
-        renderer_vulkan/vk_staging_buffer_pool.h
-        renderer_vulkan/vk_state_tracker.cpp
-        renderer_vulkan/vk_state_tracker.h
-        renderer_vulkan/vk_swapchain.cpp
-        renderer_vulkan/vk_swapchain.h
-        renderer_vulkan/vk_texture_cache.cpp
-        renderer_vulkan/vk_texture_cache.h
-        renderer_vulkan/vk_texture_cache_base.cpp
-        renderer_vulkan/vk_turbo_mode.cpp
-        renderer_vulkan/vk_turbo_mode.h
-        renderer_vulkan/vk_update_descriptor.cpp
-        renderer_vulkan/vk_update_descriptor.h
-        vulkan_common/vulkan_debug_callback.cpp
-        vulkan_common/vulkan_debug_callback.h
-        vulkan_common/vulkan_device.cpp
-        vulkan_common/vulkan_device.h
-        vulkan_common/vulkan_instance.cpp
-        vulkan_common/vulkan_instance.h
-        vulkan_common/vulkan_library.cpp
-        vulkan_common/vulkan_library.h
-        vulkan_common/vulkan_memory_allocator.cpp
-        vulkan_common/vulkan_memory_allocator.h
-        vulkan_common/vulkan_surface.cpp
-        vulkan_common/vulkan_surface.h
-        vulkan_common/vulkan_wrapper.cpp
-        vulkan_common/vulkan_wrapper.h
-        vulkan_common/nsight_aftermath_tracker.cpp
-        vulkan_common/nsight_aftermath_tracker.h
-        vulkan_common/vma.h
-        vulkan_common/vulkan.h
-    )
-endif()
 
 target_link_libraries(video_core PUBLIC common core)
 target_link_libraries(video_core PUBLIC glad shader_recompiler stb bc_decoder gpu_logging)
@@ -383,9 +384,6 @@ endif()
 if (ENABLE_OPENGL)
     target_compile_definitions(video_core PUBLIC HAS_OPENGL)
 endif()
-if (ENABLE_VULKAN)
-    target_compile_definitions(video_core PUBLIC HAS_VULKAN)
-endif()
 
 if (ARCHITECTURE_x86_64)
     target_link_libraries(video_core PUBLIC xbyak::xbyak)
diff --git a/src/video_core/video_core.cpp b/src/video_core/video_core.cpp
index 947909bfa4..fd91ee1667 100644
--- a/src/video_core/video_core.cpp
+++ b/src/video_core/video_core.cpp
@@ -18,9 +18,7 @@
 #ifdef HAS_OPENGL
 #include "video_core/renderer_opengl/renderer_opengl.h"
 #endif
-#ifdef HAS_VULKAN
 #include "video_core/renderer_vulkan/renderer_vulkan.h"
-#endif
 #include "video_core/video_core.h"
 
 namespace {
@@ -34,10 +32,8 @@ std::unique_ptr<VideoCore::RendererBase> CreateRenderer(Core::System& system, Co
     case Settings::RendererBackend::OpenGL_SPIRV:
         return std::make_unique<OpenGL::RendererOpenGL>(emu_window, device_memory, gpu, std::move(context));
 #endif
-#ifdef HAS_VULKAN
     case Settings::RendererBackend::Vulkan:
         return std::make_unique<Vulkan::RendererVulkan>(emu_window, device_memory, gpu, std::move(context));
-#endif
     case Settings::RendererBackend::Null:
         return std::make_unique<Null::RendererNull>(emu_window, gpu, std::move(context));
     default:
diff --git a/src/yuzu/bootmanager.cpp b/src/yuzu/bootmanager.cpp
index ca7150959f..8b340cb877 100644
--- a/src/yuzu/bootmanager.cpp
+++ b/src/yuzu/bootmanager.cpp
@@ -269,13 +269,11 @@ private:
     std::unique_ptr<Core::Frontend::GraphicsContext> context;
 };
 
-#ifdef HAS_VULKAN
 struct VulkanRenderWidget : public RenderWidget {
     explicit VulkanRenderWidget(GRenderWindow* parent) : RenderWidget(parent) {
         windowHandle()->setSurfaceType(QWindow::VulkanSurface);
     }
 };
-#endif
 
 struct NullRenderWidget : public RenderWidget {
     explicit NullRenderWidget(GRenderWindow* parent) : RenderWidget(parent) {}
@@ -1027,16 +1025,11 @@ bool GRenderWindow::InitializeOpenGL() {
 }
 
 bool GRenderWindow::InitializeVulkan() {
-#ifdef HAS_VULKAN
     auto child = new VulkanRenderWidget(this);
     child_widget = child;
     child_widget->windowHandle()->create();
     main_context = std::make_unique<DummyContext>();
     return true;
-#else
-    QMessageBox::warning(this, tr("Vulkan not available!"), tr("Eden has not been compiled with Vulkan support."));
-    return false;
-#endif
 }
 
 void GRenderWindow::InitializeNull() {
diff --git a/src/yuzu/main_window.cpp b/src/yuzu/main_window.cpp
index d7d5ed2958..3ecaf57087 100644
--- a/src/yuzu/main_window.cpp
+++ b/src/yuzu/main_window.cpp
@@ -3773,19 +3773,28 @@ void MainWindow::OnToggleAdaptingFilter() {
 
 void MainWindow::OnToggleGraphicsAPI() {
     auto api = Settings::values.renderer_backend.GetValue();
-    bool api_set = false;
-#ifdef HAS_VULKAN
-    if (api != Settings::RendererBackend::Vulkan) {
-        api = Settings::RendererBackend::Vulkan;
-        api_set = true;
-    }
-#endif
-    if (!api_set) {
+    switch (api) {
 #ifdef HAS_OPENGL
+    case Settings::RendererBackend::Vulkan:
         api = Settings::RendererBackend::OpenGL_GLSL;
+        break;
+    case Settings::RendererBackend::OpenGL_GLSL:
+        api = Settings::RendererBackend::OpenGL_GLSL;
+        break;
+    case Settings::RendererBackend::OpenGL_SPIRV:
+        api = Settings::RendererBackend::OpenGL_GLASM;
+        break;
+    case Settings::RendererBackend::OpenGL_GLASM:
+        api = Settings::RendererBackend::Null;
+        break;
 #else
+    case Settings::RendererBackend::Vulkan:
         api = Settings::RendererBackend::Null;
+        break;
 #endif
+    case Settings::RendererBackend::Null:
+        api = Settings::RendererBackend::Vulkan;
+        break;
     }
     Settings::values.renderer_backend.SetValue(api);
     renderer_status_button->setChecked(api == Settings::RendererBackend::Vulkan);
diff --git a/src/yuzu/startup_checks.cpp b/src/yuzu/startup_checks.cpp
index ec321555ab..9588441d78 100644
--- a/src/yuzu/startup_checks.cpp
+++ b/src/yuzu/startup_checks.cpp
@@ -19,15 +19,12 @@
 #endif
 
 #include <fmt/core.h>
-#ifdef HAS_VULKAN
 #include "video_core/vulkan_common/vulkan_wrapper.h"
 #include "video_core/vulkan_common/vulkan_instance.h"
 #include "video_core/vulkan_common/vulkan_library.h"
-#endif
 #include "yuzu/startup_checks.h"
 
 void CheckVulkan() {
-#ifdef HAS_VULKAN
     // Just start the Vulkan loader, this will crash if something is wrong
     try {
         Vulkan::vk::InstanceDispatch dld;
@@ -38,7 +35,6 @@ void CheckVulkan() {
     } catch (const Vulkan::vk::Exception& exception) {
         fmt::print(stderr, "Failed to initialize Vulkan: {}\n", exception.what());
     }
-#endif
 }
 
 bool CheckEnvVars(bool* is_child) {
diff --git a/src/yuzu/vk_device_info.cpp b/src/yuzu/vk_device_info.cpp
index 31f4dee1c1..a82a50c48c 100644
--- a/src/yuzu/vk_device_info.cpp
+++ b/src/yuzu/vk_device_info.cpp
@@ -11,13 +11,11 @@
 
 #include "common/dynamic_library.h"
 #include "common/logging/log.h"
-#ifdef HAS_VULKAN
 #include "video_core/vulkan_common/vulkan_device.h"
 #include "video_core/vulkan_common/vulkan_instance.h"
 #include "video_core/vulkan_common/vulkan_library.h"
 #include "video_core/vulkan_common/vulkan_surface.h"
 #include "video_core/vulkan_common/vulkan_wrapper.h"
-#endif
 #include "vulkan/vulkan_core.h"
 #include "yuzu/vk_device_info.h"
 
@@ -30,9 +28,7 @@ Record::Record(std::string_view name_, const std::vector<VkPresentModeKHR>& vsyn
 
 Record::~Record() = default;
 
-void PopulateRecords(std::vector<Record>& records, QWindow* window)
-#ifdef HAS_VULKAN
-try {
+void PopulateRecords(std::vector<Record>& records, QWindow* window) try {
     using namespace Vulkan;
 
     // Create a test window with a Vulkan surface type for checking present modes.
@@ -80,8 +76,5 @@ try {
 } catch (const Vulkan::vk::Exception& exception) {
     LOG_ERROR(Frontend, "Failed to enumerate devices with error: {}", exception.what());
 }
-#else
-{}
-#endif
 
 } // namespace VkDeviceInfo